ABSTRACT. The present study aimed to evaluate the in vitro antimicrobial activity of pharmacologically important Adhatoda vasica plant extracts. Plant Adhatoda vasica L. Nees (Acanthaceae) commonly known as Malabar nut is an evergreen two – three m tall shrub, sometime used as. Adhatoda vasica (L.) (Acanthaceae) is used in the indigenous system of medicine in India. The alkaloid Vasicine was isolated from ethanolic extract of the .
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Essential oils of the leaves of A.
The fraction was further purified and the compound Vasicine was isolated. Published online Jan Medicinal plants are important sources of practical drugs for people throughout the year.
Journal List Biomed Res Int v. Extraction Shade dried and coarsely powdered leaves of A. Preliminary phytochemical and antibacterial screening of crude extract of the leaf of Adhatoda vasica.
Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper
The combined chloroform extract was washed with water, dipped, and dried over anhydrous sodium sulphate. The MIC for bacteria was determined as the lowest concentration of the compound inhibiting the visual growth of the test cultures on the agar plate. Other constituents include vitamin C, vawica, flavonoids as well as steroids, and fatty acids [ 13 ].
The physical and spectroscopic data were compared with those reported in the literature [ 15 ].
antlmicrobial Then the residue was crystallised from chloroform to get Vasicine acetate as colorless crystals m. Minimum inhibitory concentration of Vasicine acetate against tested bacteria and fungi. The free radical scavenging activity was calculated as follows:. Abstract Adhatoda vasica L. Vasicine acetate could be checked further in drug discovery programme.
The chemicals are given in delta scale with TMS as an internal standard. Cytotoxic A and antimicrobial effects of Methylobacterium sp. Handbook of Ayurvedic Medicinal Plants.
Vasicine acetate could be probed further in drug discovery programme. The alkaloid Vasicine antimlcrobial isolated from ethanolic extract of the leaves of A. Separation was carried out at room temperature.
Antibacterial Activity of Leaf Extracts of Adhatoda vasica – MAHE Digital Repository
BoxRiyadhSaudi Arabia. A human vasifa cancer cell line was obtained from National Institute of Cell Sciences, Pune. BHT is used as standard of antioxidant. Vasicine acetate showed moderate antibacterial activity compared to Vasicine. The plant is used in the indigenous system of medicine in India and is a well-known expectorant in both Ayurvedic and Unani Systems of Medicine [ 45 ]. Vasicine acetate exhibited good zone of inhibition against bacteria: Table 4 Cytotoxic effect of Vasicine acetate against A lung adenocarcinoma cancer cell line.
The required concentrations, ,