os riscos das condições orais e sistêmicas que envolvem o uso de bifosfonatos. para tratar a estos pacientes en las distintas especialidades odontologicas. Sobre el 70% de los casos se produce después de un procedimiento dental Palabras clave: osteonecrosis, bifosfonatos, osteonecrosis de los maxilares. La prevalencia de avulsión dental supone del 0, % de todas las lesiones .. (58), acetazolamida (59), bifosfonatos (60,61)o derivado de la matriz del.

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Sociedad de Periodoncia de Chile. Los resultados indican, que los pacientes en mayor riesgo de desarrollar osteonecrosis de los maxilares son aquellos que reciben terapia con bifosfonatos nitrogenados intravenosos.

El manejo de las lesiones es odomtologia alta complejidad. Bifosronatos recent years, due to different causes, an increasing number of patients are under medical treatment with bisphosphonates. These drugs might be associated with the growing of spontaneous ulceration of the oral mucosa and osteonecrosis of the jaws.

The purpose of this review is to describe the characteristics of bisphosphonates, its mechanism of action, clinical manifestation of osteonecrosis of the jaws, therapeutic management and prevention.

Patients treated with intravenous nitrogen-containing bisphosphonates, have a major risk to develop osteonecrosis. The mandible is more commonly affected than the maxilla. Probably the origin of the biifosfonatos of the jaws is a decreased microcirculation and a limited bone turnover due to bisphosphonates, leading to diminish their healing capacity and regeneration of the tissues. The management of the lesions is difficult. Palliative treatment is proposed with oral rinses and systemic antibiotic therapy.

Removal of necrotic bone is recommended in severe cases. In conclusion, is necessary to know this condition for an early diagnosis and treatment, so to prevent its apparition. In this way, it is recommendable to do an oral examination and odontoologia, to treat active oral infections and eliminate sites at high risk for infection before getting the bisphosphonate therapy started.


Furthermore, to avoid surgical procedures in risky patients. Scielo, ScienceDirect, Latindex, Redalyc.

Tratamiento de la litiasis renal con bifosfonatos

Osteonecrosis de los Maxilares Asociado a Terapia con Bifosfonatos: Abstract In recent years, due to different causes, an increasing number of bifosfonato are under medical treatment with bisphosphonates. CMAJ,pp. The use of bisphosphonates in elderly cancer patients. Oncologist, 12pp. A review of Bisphosphonate-associated osteonecrosis of the jaws and its management.

Osteonecrosis de los Maxilares Asociado a Terapia con Bifosfonatos: Situación Actual

JCDA, 73pp. Pamidronate Aredia and Zolendronate Zometa induced avascular necrosis of the jaws: J Oral Maxillofac Surg, 61 bifosofnatos, pp. Bisphosphonates and oral cavity avascular bone necrosis. J Clin Oncol, 21pp.

Osteonecrosis of the jaws associated with the use of Bisphosphonates: A review of 63 cases. J Oral Maxillofac Surg, 62pp. Avascular jaw Osteonecrosis in association with cancer chemotherapy: J Oral Pathol Med, 34pp.

Bisphosphonate-induced avascular osteonecrosis of the jaws: Int J Oral Maxillofac Surg, 35pp. Quim Nova, 28pp. Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone reorption by preventing protein prenylation: J Bone Miner Res, 13pp. Bisphosphonates and osteonecrosis of the jaws: Implants and oral bisphosphonates: J Periodontol, 78pp. J Oral Maxillofac Surg, 63pp. Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment.

J Clin Periodontol, 32pp.

Novel antiogenic effects of the bisphosphonate compound Zoledronic acid. JPET,pp. Patients with bisphosphonates-associated osteonecrosis of the jaw have reduced circulating endothelial cells. Hematol Oncol en prensa. Endocrine Reviews, 19pp. Effect of long—term oral bisphosphonates on implant wound healing: Nitrogen-containing bisphosphonates inhibit the Mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Osteonecrosis associated with the use of biphosphonates: Rev Med Chile,pp.

Managing the care of patients with bisphosphonate-associated osteonecrosis: J Am Dent Assoc,pp. Nature and frequency of bisphosphonateassociated osteonecrosis of the jaws in Australia. J Oral Maxillofac Surg, 65pp. Bisphosphonate-associated osteonecrosis of the jaws Report of a case and literature review.


Implant placement with or without simultaneous tooth extraction in patients taking oral bisphosphonates: Oral and intravenous bisphosphonates induced osteonecrosis of the jaws History, etiology, prevention and treatment. Quintessence Publishing Co Inc,pp. Osteonecrosis bifofsonatos the jaw and bisphosphonates.

N Engl J Med,pp. Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: J Clin Oncol, 23pp.

Osteonecrosis of the jaws: J Intern Med,pp. Bisphosphonate-associated ovontologia of the jaws: Osteonecrosis of the jaws and bisphosphonates Report of three cases.

Int J Oral Maxillofac Implants, 22pp. Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy. J Periodontol, 77pp. Int J Periodontics Restorative Dent, 26pp. Safety of oral bisphosphonates: Int J Oral Maxillofac Implants, 21pp. Orthodontic treatment of patients using bisphosphonates: A report of 2 cases.

Am J Orthod Bjfosfonatos Orthop,pp. Bisphosphonate-associated osteonecrosis of the jaws and endodontic treatment: J Endod, 31pp.

BIFOSFONATO FINAL by Fabiola González on Prezi

Endodontic implications of bisphosphonate-associated osteonecrosis of the jaws: N Eng J Med,pp. Posible association between diabetes and bisphosphonate-related jaw osteonecrosis. J Clin Endocrinol Metab, 92pp. Bisphosphonate therapy improves the outcome of conventional periodontal treatment: J Periodontol, 76pp.

Effect of topical administration of monosodium olpadronate on experimental periodontitis in rats. The bisphosphonate ibandronate accelerates osseointegration of hydroxyapatite-coated cementless implants in an animal model.

J Orthop Sci, 12pp. The bisphosphonate pamidronate on the surface of titanium stimulates bitosfonatos formation around tibial implants in rats. Biomaterials, 26pp. Boosting effect of bisphosphonates on osteoconductive materials: J Periodont Res, 42pp.

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